Dr. Bruno’s Translational Cardio-Immunology Research Laboratory engages in five primary research focus areas:
- Identifying novel immunomechanisms contributing to myocarditis, dilated cardiomyopathy and heart failure utilizing new animal models of disease
- Understanding how sex and age differences contribute to mechanisms of diseases
- Identifying biomarkers and therapies that improve the diagnosis and treatment of cardiac conditions
- Studying how chemotherapy drugs can cause heart failure and find tools to predict and prevent it
- Utilize patient samples and data to confirm findings in mouse and cell culture models, emulating “Bench to Bedside”
Funded Research Projects
- Vitamin D binding protein (DBP) in innate immune cell response in viral myocarditis
- National Institute of Allergy and Infectious Diseases (NIAID)
- Principle Investigator
- Sex differences in novel viral myocarditis therapeutic: adipose-derived stem cell secretome
- American Heart Association
- Principle Investigator
- Characterization of TRPC6 to predict and prevent chemotherapy-related cardiomyopathy and heart failure in women
- Department of Defense
- University of Florida Site Principle Investigator (Grant Co-Investigator)